Anti-GBM rapidly progressive glomerulonephritis (Syndroma Goodpasture): A case report
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چکیده
منابع مشابه
A Case of Membranous Glomerulonephritis with Superimposed Anti-Neutrophil Cytoplasmic Antibody-Associated Rapidly Progressive Crescentic Glomerulonephritis
Idiopathic membranous glomerulonephritis (IMGN) is commonly diagnosed in adults with proteinuria. Rapid deterioration of renal function is a rare complication of IMGN, except when accompanied by renal vein thrombosis, malignant hypertension, or other underlying disease, including lupus nephritis. Here, we present a case of rapid deterioration of renal function in a patient with MGN superimposed...
متن کاملRapidly Progressive Glomerulonephritis
Rapidly Progressive Glomerulonephritis are a group of renal diseases which are still posing serious threat to human health and survival. They are all characterised by acute and rapid deterioration of renal function. Renal biopsy reveals extracapillary glomerulonephritis, most frequently circumferential and diffuse, and immunofluorescence findings continue to represent the most important clue to...
متن کاملAnti-GBM crescentic glomerulonephritis with intensive multinucleated giant cells: a case report
Anti-glomerular basement membrane (anti-GBM) disease is a rare but potentially lethal autoimmune disorder with progressive renal dysfunction in a short time span, which is accompanied with or without pulmonary hemorrhage. Serologic test shows positive anti-GBM antibodies, and extensive crescent formation in the renal biopsy, usually without multinucleated giant cells. Our study presents a case ...
متن کاملAnti-GBM antibodies in Goodpasture syndrome; anatomy of an epitope.
like group (comprising a-2(IV ) itself, a-4(IV ), and Introduction a-6(IV )). Basement membranes are thin sheet-like extracellular The six a(IV ) chains di er considerably from each structures that form an anatomical barrier wherever other in their tissue distribution. The a-1( IV ) and cells meet connective tissue. They provide a substrate a-2(IV ) chains are found in all basement membranes, f...
متن کاملMolecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
BACKGROUND In Goodpasture's disease, circulating autoantibodies bind to the noncollagenous-1 (NC1) domain of type IV collagen in the glomerular basement membrane (GBM). The specificity and molecular architecture of epitopes of tissue-bound autoantibodies are unknown. Alport's post-transplantation nephritis, which is mediated by alloantibodies against the GBM, occurs after kidney transplantation...
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ژورنال
عنوان ژورنال: Serbian Journal of Experimental and Clinical Research
سال: 2014
ISSN: 1820-8665
DOI: 10.5937/sjecr1403157f